Disease

AS (Ankylosing Spondylitis)

Description

Ankylosing spondylitis is a form of arthritis that affects the spine and is a chronic condition. The term is derived from two Greek words that mean "bent spine inflammation." It causes painful inflammation of the joints between the vertebrae in the spine and between the spine and pelvis. In advanced cases, it can cause the vertebrae to fuse together, further limiting movement and resulting in a hunched over posture. Occasionally it can involve other joints or organs in the body as well.

Ankylosing spondylitis affects men more than women and is usually diagnosed during the teenage years, twenties, or thirties. People with a gene called HLA-B27 are at significantly increased risk of developing the condition. However, being born with this gene doesn't necessarily lead to ankylosing spondylitis and scientists are currently researching other suspected triggers.
 


Related Test

Full Blood Count (FBC)
C-reactive protein (CRP) 
Erythrocyte sedimentation rate (ESR) 
HLA-B27


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