Disease

Autoimmune Thyroiditis (Hashimoto Thyroiditis)

Description

Hashimoto thyroiditis is the most common form of thyroid gland inflammation (thyroiditis) and the most frequent cause of decreased thyroid hormone production (hypothyroidism). It results from an autoimmune disorder, an attack on the thyroid gland by a person's own immune system.

The thyroid gland is a butterfly-shaped organ that lies flat against the windpipe in the throat. It produces the hormones thyroxine (T4) and triiodothyronine (T3) and plays an important role in controlling the body's metabolism.

With Hashimoto thyroiditis, the thyroid becomes enlarged (called a goiter), firm, and rubbery but not usually tender. Thyroid gland tissue is slowly destroyed by white blood cells called lymphocytes that move into the thyroid gland and by one or more thyroid autoantibodies. This causes a progressive decrease in the production of thyroid hormones.


Related Test

Thyroid-stimulating hormone (TSH) 
Free T4
Free T3 
Anti-thyroid peroxidase antibody (anti-TPO)
Antithyroglobulin antibody (TgAb) 


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