Disease

Antiphospholipid Syndrome (aCL Syndrome)

Description

Antiphospholipid syndrome (APS) is an autoimmune disorder, meaning that the body's immune system makes proteins known as antibodies that mistakenly attack its own cells or tissues. The syndrome is associated with risk of inappropriate blood clot formation, so it is considered an excessive clotting disorder (thrombophilia).


Related Test

Lupus anticoagulant testing (e.g., dilute Russell viper venom test or DRVVT and hexagonal phase phospholipid neutralization test)
Cardiolipin antibodies
Beta2 glycoprotein I (β2GP1) antibodies

Partial thromboplastin time (PTT)
Prothrombin time (PT)
Complete blood count (CBC), to evaluate blood cells and platelets
A variety of additional tests to evaluate other causes of a person's symptoms, such as 1:1 Mix study (dilute PTT) to screen for lupus anticoagulant in the blood


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