Test/Profile NameAnti Mitochondrial Antibody
Antimitochondrial antibodies (AMA) are autoantibodies that are strongly associated with primary biliary cholangitis (PBC), formerly called primary biliary cirrhosis. Primary biliary cholangitis is a chronic autoimmune disorder that causes inflammation and scarring of the bile ducts inside the liver. It is a slow-progressing disease that causes worsening liver destruction (may eventually lead to permanent scarring (cirrhosis)) and blockage of the bile flow. PBC is found most frequently in women between the ages of 35 and 60. About 90-95% of those affected by PBC will have significant titers of antimitochondrial antibodies. The presence of the M2 type of AMA has been particularly evident in PBC.
Specimen Type and Minimal VolumeVariable Please confirm with the laboratory prior to testing.